GWAS standardisationFunctions for standardising GWAS inputs |
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GWAS object |
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ColumnMap object |
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Column object |
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Liftover GWAS positions |
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as.data.table |
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GWAS processingFunctions for prosessing GWAS data |
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Clump a GWAS |
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Harmonise GWAS effects |
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Calculate LD matrix |
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Extract variants from plink binary |
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Get proxies for variants from plink binary |
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subset_gwas |
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Mendelian RandomizationFunctions for performing MR |
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MR object |
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Reset index SNP |
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Clump MR object exposure |
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Run Egger MR |
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Run IVW MR |
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Run PC-GMM MR |
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MR results to data.table |
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Run weighted median MR |
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Run weighted mode MR |
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Run MR |
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Plot MR results |
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Set the LD matrix |
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Convert to MendelianRandomization::MRInput object |
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Convert to MendelianRandomization::MRMVInput object |
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Calculate LD matrix |
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RSID mappingFunctions for mapping chromosome and position data to variant RSIDs |
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Chromosome & position data to variant RSID |
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Collider biasFunctions for analysing collider / index event bias and adjust GWAS data for this bias. |
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Run collider bias assessment |
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Corrected Weighted Least Squares collider bias method |
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Slope-Hunter collider bias method |
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Dudbridge collider bias method |
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PlottingFunctions for creating common GenEpi data plots |
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Manhattan plot |
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Miami plot |
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QQ plot |
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Effect allele frequency plot |
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Generate random GWAS data |
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Coloc probability plot |
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SetupFunctions for package configuration |
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Set dbSNP directory |
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Get available dbSNP builds |
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Get dbSNP directory |
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Set the 1000G reference path |
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Set the PLINK2 path |
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Get 1000G reference path(s) |
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Get plink2 path |